Complete physician-supervised TRT with full peptide support layer. Gonadorelin preserves LH pulse and testicular function. Comprehensive blood work monitoring throughout.
The TRT Full Clinic Protocol differs from the TRT Companion Protocol in scope. The companion protocol assumes you are already on TRT and adds peptide support. This protocol covers the full clinical picture — from blood test confirmation of hypogonadism, through dose titration, HPG axis preservation, and the complete peptide support layer.
Gonadorelin is central to this protocol. Without it (or hCG, which it largely replaces in modern TRT practice), the testes atrophy within months and fertility potential is lost. In clinical practice, Gonadorelin is now preferred over hCG for HPG preservation — it works upstream at the pituitary, producing a more physiological LH pulse pattern.
Some men on TRT require an aromatase inhibitor to manage oestradiol (E2) conversion. This protocol includes E2 monitoring but not a standard AI in the stack — AI use should be individualised based on blood test results. Inappropriate AI use (over-suppressing E2) causes joint pain, mood disorders, and cardiovascular risk. Aim to manage E2 to the middle of the reference range, not suppress it.
This is the most blood-work-intensive protocol on Pep IQ. Seven panels in the first year of initiation: months 1, 2, 3, 4 (trough), 6, 9, 12. Once stable, quarterly thereafter. Core panel: Total T, Free T, E2, LH (to confirm Gonadorelin working), FSH, SHBG, PSA (45+), haematocrit, lipid panel, liver function. Always test at trough — 48 hours post injection for cypionate/enanthate.
Full dosing, titration schedule, blood work timing and cycling notes are available inside the platform. Use the calendar to track your protocol.