✦ PeptideWorld · Issue 01
Live now: April to May 2026 peptide news roundup — FDA reclassification, retatrutide TRIUMPH-1, Foundayo approval, UK MHRA, safety signals.
Read Issue 01 →
UK legal status key
Legal to possess — not a controlled drug, no prescription needed
Prescription-only medicine — legal, but UK supply needs a prescription
Controlled drug — possession or supply restricted under UK law
Colours show UK legal status only — not safety, effectiveness, or a recommendation to use.
PART ONE
Healing & Recovery Peptides
Peptides for tissue repair, injury recovery, gut healing, and immune support
10 of 10 liveP1 — 01
BPC-157
Body Protection Compound
UK · legal to buy or possess
·Gut healing · tendon/ligament repair · soft tissue
·250–500 mcg · oral or SubQ · daily or split
·500+ animal studies · community use
P1 — 02
TB-500
Thymosin Beta-4 Fragment · LKKTETQ
UK · legal to buy or possess
·Soft tissue · tendon · muscle recovery
·2–5 mg/week · SubQ or IM · cycled
·Community use · often sold as TB-4
P1 — 03
KPV
Lys-Pro-Val · α-MSH Fragment
UK · legal to buy or possess
·Anti-inflammatory · gut · skin
·0.5–1 mg · oral or topical · daily
·Strong preclinical · oral · community use
P1 — 04
Collagen Peptides
Hydrolysed Collagen · Types I/II/III
UK · legal to buy or possess
·Skin · joints · tendons · bone
·10–20 g · oral · daily
·Multiple RCTs · food supplement
P1 — 05
Thymosin α-1
Thymalfasin · Zadaxin · Tα1
UK · legal to buy or possess
·Immune · oncology adjunct · hep B
·1.6 mg · SubQ · 2× weekly
·30+ trials · 35+ country approval
P1 — 06
Thymulin
FTS · Zn-FTS · Thymic Factor
UK · legal to buy or possess
·Thymic · immune · analgesic
·Preclinical doses · zinc-dependent
·1982 single trial · animal data
P1 — 07
Thymalin
Calf Thymus Polypeptide · Russian
UK · legal to buy or possess
·Immune · post-surgery · hepatitis
·5–20 mg · IM · 5–10 day course
·Russian clinical use · decades · no Western RCT
P1 — 08
Cartalax
AED · Ala-Glu-Asp · Cytomedin
UK · legal to buy or possess
·Cartilage · joint · chondrocyte
·5–10 mg · SubQ · 10-day course
·Russian preclinical · no Western RCT
P1 — 09
Arg-BPC-157
Arginine Salt · Oral BPC-157
UK · legal to buy or possess
·Gut healing · oral BPC-157 · stable
·250–500 mcg · oral · 1–2× daily
·Inherits BPC-157 data · community use
P1 — Blend
Klow Blend
BPC-157 · TB-500 · GHK-Cu · KPV
UK · legal to buy or possess
Glow Blend plus KPV — adds dedicated NF-kB inflammation control. Four-compound stack for recovery, skin quality, and chronic inflammation management. 80mg total. KPV and BPC-157 can be taken orally.
More Info →
P1 — 10
Larazotide
AT-1001 · Zonulin Antagonist
UK · legal to buy or possess
·Gut barrier · tight junction · leaky gut
·0.5 mg oral · pre-meal · 3× daily
·Phase 3 celiac · Phase 2 MIS-C
P1 — Blend
Glow Blend
BPC-157 · TB-500 · GHK-Cu
UK · legal to buy or possess
Community biohacker combination targeting tissue repair, cell migration, and collagen remodelling. GHK-Cu dominant at 50mg (5:1:1 ratio). Single vial, one daily injection. 80mg total.
More Info →
PART TWO
Metabolic, Weight & GH Peptides
Peptides for fat loss, body composition, blood sugar, and the growth hormone axis
16 of 16 liveP2 — 01
GLP-1
Semaglutide · Ozempic · Wegovy
UK · prescription only medicine
·Weight loss · cardio · diabetes
·Weekly SubQ · titrated · MHRA-licensed
·Phase III RCTs · clinical use
P2 — 02
Semaglutide
Ozempic · Wegovy · Rybelsus
UK · prescription only medicine
·Weight loss · cardio · diabetes
·0.25–2.4 mg · SubQ · weekly titration
·SELECT trial · Phase III RCTs
P2 — 03
Tirzepatide
Mounjaro · Zepbound · GIP/GLP-1 RA
UK · prescription only medicine
·Weight loss · diabetes · sleep apnoea
·2.5–15 mg · SubQ · weekly titration
·2025 NEJM head-to-head · Phase III
P2 — 04
AOD-9604
HGH Fragment 176–191
UK · legal to buy or possess
·Fat loss · lipolysis · cartilage repair
·250–500 mcg · SubQ · daily fasted
·Animal + Phase II · community use
P2 — 05
IGF-1
Insulin-Like Growth Factor 1
UK · legal to buy or possess
·Anabolic · growth · recovery
·0.04–0.12 mg/kg · SubQ · 2× daily
·FDA approved · Increlex · clinical use
P2 — 06
Tesamorelin
EGRIFTA · EGRIFTA WR · TH9507
UK · prescription only medicine
·Visceral fat · GH axis · lipodystrophy
·1–2 mg · SubQ · daily
·Phase III RCT · clinical use
P2 — 07
Sermorelin
GHRH (1–29) · Geref
UK · legal to buy or possess
·GH axis · sleep · body composition
·100–300 mcg · SubQ · pre-bed
·FDA approved · community use
P2 — 08
CJC-1295
DAC:GRF · Long-acting GHRH
UK · legal to buy or possess
·GH baseline · long-acting · weekly
·1–2 mg · SubQ · 1–2× weekly
·Phase II data · community use
P2 — 09
Ipamorelin / CJC-1295
NNC 26-0161 · DAC:GRF · GH Stack
UK · legal to buy or possess
·GH pulse · muscle · fat loss
·100/100 mcg · SubQ · 1–3× daily
·Phase II data · community use
P2 — 10
Mod-GRF 1-29
CJC-1295 no DAC · Mod GRF 1-29
UK · legal to buy or possess
·GH pulse · pulsatile · physiological
·100 mcg · SubQ · 2–3× daily
·Mechanism · community use
P2 — 11
GHRP-2 / GHRP-6
Pralmorelin · Hexapeptide GHRPs
UK · legal to buy or possess
·GH pulse · appetite · first-gen
·100 mcg · SubQ · 1–3× daily
·Early human · community use
P2 — 12
MGF / PEG-MGF
Mechano Growth Factor · IGF-1Ec
UK · legal to buy or possess
·Muscle repair · satellite cells · local growth
·200–400 mcg · SubQ near-site · post-workout
·Animal data · community use
P2 — 13
IGF-1 LR3
Long Arg3 IGF-1 · R3-IGF-1
UK · legal to buy or possess
·Muscle · hypertrophy · recovery
·20–100 mcg · SubQ · post-workout
·Animal data · community use
P2 — 15
Retatrutide
LY3437943 · GLP-1/GIP/Glucagon
UK · legal to buy or possess
·Weight loss · liver fat · diabetes
·4–12 mg · SubQ · weekly
·Phase 3 TRIUMPH · approval ~2027
P2 — 16
HGH Fragment 176–191
HGH Frag · GH C-terminal Fragment
UK · legal to buy or possess
·Fat loss · lipolysis · no IGF-1 path
·250–500 mcg · SubQ · 2–3× daily
·Animal data · community use
PART THREE
Mitochondrial Peptides
Peptides targeting mitochondrial function, energy production, and cellular longevity
6 of 6 liveP3 — 01
SS-31
Elamipretide · MTP-131 · Bendavia
UK · prescription only medicine
·Mitochondrial · cardiac · longevity
·40 mg · SubQ · daily
·Phase III RCTs · FDA-approved 2025
P3 — 02
MOTS-c
Mitochondrial ORF of the 12S rRNA-c
UK · legal to buy or possess
·Metabolic · exercise mimetic · insulin support
·5–10 mg · SubQ · 2–3× weekly
·Animal data · early human · community use
P3 — 03
Humanin
HN · Mitochondria-Derived Peptide
UK · legal to buy or possess
·Neuro · longevity · metabolic
·Human dose unsettled
·Animal + centenarian
P3 — 04
5-Amino-1MQ
NNMT Inhibitor · NAD+ Amplifier
UK · legal to buy or possess
·NAD+ · brown fat · adiposity
·50–150 mg · oral · daily (community)
·Animal · community use
P3 — 05
AICAR
5-AICA Riboside · AMPK Activator
UK · legal to buy or possess
·AMPK · endurance · fat oxidation
·Human dose unsettled · WADA prohibited
·Animal Cell 2008 · no human safety
P3 — 06
NAD+ / NMN / NR
Nicotinamide Adenine Dinucleotide
UK · legal to buy or possess
·Energy · sirtuins · DNA repair
·250–1000 mg · oral · daily
·Growing RCT base · supplement form
PART FOUR
Cognitive & Neurological Peptides
Peptides for cognition, neuroprotection, anxiety, and sleep
8 of 8 liveP4 — 01
Semax
MEHFPGP · ACTH(4-7)PGP
UK · legal to buy or possess
·Cognition · focus · neuroprotect
·0.6–1 mg · intranasal · daily
·Russian clinical · community use
P4 — 02
Selank
TKPRPGP · Tuftsin Analogue
UK · legal to buy or possess
·Anxiety · cognition · mood
·250–900 mcg · intranasal · daily
·Russian RCT · community use
P4 — 03
Adamax
N-Acetyl Semax Adamantane
UK · legal to buy or possess
·Nootropic · BBB penetration · cognitive
·Human dose unsettled
·Inferred from Semax · no human RCT
P4 — 04
Cerebrolysin
Porcine Brain Peptide Mix · CBL
UK · legal to buy or possess
·Stroke · dementia · cognition
·5–30 mL · IV/IM · 10–20 day course
·Clinical RCTs · 50+ country approval
P4 — 05
DSIP
Delta Sleep Inducing Peptide
UK · legal to buy or possess
·Sleep depth · stress · recovery
·100–500 mcg · SubQ or nasal · pre-bed
·50yr research · community use
P4 — 06
Pinealon
EDR · Glu-Asp-Arg
UK · legal to buy or possess
·Neuro · sleep · circadian
·5–10 mg · SubQ · 10-day course
·Russian preclinical · no Western RCT
P4 — 07
VIP
Vasoactive Intestinal Peptide
UK · legal to buy or possess
·Anti-inflammatory · CIRS · pulmonary
·50 mcg · intranasal · 4× daily (Shoemaker)
·Clinical use · CIRS protocol · trial data
P4 — 08
N-Acetyl Semax Amidate
NA Semax Amidate · Enhanced Semax
UK · legal to buy or possess
·Nootropic · BDNF · neuroprotection
·300–600 mcg · intranasal · daily
·Inherits Semax data · community use
PART FIVE
Longevity, Skin & Sexual Health
Peptides for anti-ageing, skin, longevity, and sexual function
8 of 8 liveP5 — 01
Epitalon
Epithalon · AEDG · Ala-Glu-Asp-Gly
UK · legal to buy or possess
·Telomere · pineal · longevity
·5–10 mg · SubQ · 10–20 day cycles
·Russian clinical · community use
P5 — 02
FOXO4-DRI
Senolytic · FOXO4-p53 Disruptor
UK · legal to buy or possess
·Senolytic · longevity · senescent cells
·1–5 mg/day · SubQ · 5-on/2-off
·Landmark Cell paper · animal data
P5 — 03
GHK-Cu
Copper Peptide · Gly-His-Lys
UK · legal to buy or possess
·Skin · wound healing · hair
·1–3 mg/day · SubQ or topical · daily
·RCT topical · community use
P5 — 09
SNAP-8
Acetyl Octapeptide-3
UK · legal to buy or possess
·Expression lines · forehead · eyes
·3–10% serum · topical · twice daily
·Manufacturer data · topical only
P5 — 04
Bremelanotide
PT-141 · Vyleesi
UK · prescription only medicine
·Desire · HSDD · ED non-responders
·1.75 mg · SubQ · on demand
·Phase III RCTs · approved (Vyleesi)
P5 — 05
Oxytocin
OXT · Pitocin · The "Love Hormone"
UK · prescription only medicine
·Bonding · anxiety · social context
·24 IU intranasal · context-dependent
·Clinical (obstetric) · RCT (psych)
P5 — 06
Melanotan II
MT-II · MT-2 · "Barbie Drug"
UK · legal to buy or possess
·Tanning · libido · appetite
·0.25–1 mg · SubQ · loading + maint
·Phase I/II trials · community use
P5 — 07
Kisspeptin-10
KP-10 · KISS1 Fragment
UK · legal to buy or possess
·HPG axis · libido · fertility
·0.1–1 mg · SubQ · pulse dose
·Human LH/T data · Phase II trials
P5 — 08
Melanotan I
Afamelanotide · Scenesse
UK · prescription only medicine
·Tanning · photoprotection · EPP
·0.5–1 mg · SubQ · loading + maintenance
·Scenesse · FDA 2019 · EPP only
PART SIX
Immune & Organ Peptides
Peptides for immune modulation, antimicrobial defence, and organ-specific tissue support
4 of 4 liveP6 — 01
LL-37
Cathelicidin · CAP-18
UK · legal to buy or possess
·Antimicrobial · wound · immunity
·100 mcg/day · SubQ · daily
·Preclinical · early human · community
P6 — 02
Thymosin β4 (Full)
Tβ4 · 43-AA · Parent of TB-500
UK · legal to buy or possess
·Cardiac · corneal · tissue repair
·2–10 mg · SubQ · weekly cycle
·Preclinical · small trials
P6 — 03
Khavinson Peptides
Bronchogen · Cardiogen · Livagen +
UK · legal to buy or possess
·Short peptide · organ-specific signal
·Oral or SubQ · 10–20 day course
·Russian clinical · 1970s+
P6 — 04
Gonadorelin
GnRH · Lutrepulse · LHRH
UK · legal to buy or possess
·HPG axis · TRT support · fertility
·100–200 mcg · SubQ · 2× weekly
·Clinical use · diagnostic + therapy
PART SEVEN
Clinical & Specialist Peptides
FDA-approved peptide drugs for specific medical conditions — context for understanding where the science has reached full clinical validation
4 of 4 liveP7 — 01
Liraglutide
Victoza · Saxenda · NN2211
UK · prescription only medicine
·Weight loss · cardio · diabetes
·0.6–3.0 mg · SubQ · daily
·Phase III RCTs · LEADER trial
P7 — 02
Hexarelin
Examorelin · EP-23905
UK · legal to buy or possess
·GH pulse · cardiac · potent
·100 mcg · SubQ · 2–3× daily
·Phase II · community use
P7 — 03
MK-677 (Ibutamoren)
Ibutamoren · MK-0677
UK · legal to buy or possess
·GH + IGF-1 · oral · 24hr
·10–25 mg · oral pill · daily
·Phase II · community use
P7 — 04
Follistatin
FST · FS-315 · FS-344
UK · legal to buy or possess
·Myostatin inhibition · muscle mass
·100 mcg · SubQ · 4–8 weeks
·Animal strong · human emerging
FRONTIER
Frontier — pre-mainstream science
Compounds Pep IQ is tracking before they reach widespread clinic or community use. Some are in late-stage trials. Some are experimental research peptides. All are watched here until they cross into mass population use — at which point they relocate to their mechanism Part. One new Coming Soon card lands each month.
11 live · 1 comingFrontier
Amycretin
NNC0174-0833 · GLP-1/Amylin Dual
UK · legal to buy or possess
·Weight loss · appetite · glucagon
·Phase II trial doses · investigational
·22% weight loss · 12-wk Phase 1
Frontier
SHLP Peptides
Small Humanin-Like · SHLP-2/6 · MDP
UK · legal to buy or possess
·Mitochondrial · longevity · glucose
·Preclinical only · no human dose
·Discovery 2023–24 · early-stage
Frontier
Dihexa
PNB-0408 · Angiotensin IV Derivative
UK · legal to buy or possess
·Cognition · memory · neuroplasticity
·8–15 mg · oral · 4–6 weeks
·Strong animal · early community
Frontier
SLU-PP-332
ERRα/γ Agonist · Exercise Mimetic
UK · legal to buy or possess
·Cardiac · exercise mimetic · endurance
·Preclinical only · no human dose
·2023 USC discovery · mouse in vivo
Frontier
CagriSema
Cagrilintide + Semaglutide 2.4mg
UK · prescription only medicine
·Weight loss · appetite · glucagon
·Phase III trial dose · investigational
·~24% weight loss · REDEFINE programme
Frontier
PE-22-28
BDNF Loop Mimetic · TrkB Activator
UK · legal to buy or possess
·Antidepressant · BDNF · neuroplasticity
·Preclinical only · no human dose
·Rodent models · no human trials
Frontier
Klotho Peptides
KL1 Peptides · αKlotho Fragments
UK · legal to buy or possess
·Cognition · longevity · ageing
·Preclinical only · no human dose
·2023–25 mouse data · emerging
Frontier
Spadin
TREK-1 Antagonist · Sortilin-Derived
UK · legal to buy or possess
·Antidepressant · TREK-1 · fast-acting
·Preclinical only · no human dose
·Animal models · novel mechanism
Frontier
Survodutide
BI 456906 · GLP-1 / Glucagon Dual
UK · legal to buy or possess
·Weight loss · MASH · liver fat
·Once weekly SubQ · Phase 3
·SYNCHRONIZE-1 · 16.6% at 76wk
Frontier
Tat-Beclin-1
Tat-BECN1 · TB-1 · Autophagy Inducer
UK · legal to buy or possess
·Autophagy · neuro · longevity
·2 mg/kg IP · rodent dose
·Animal models · Levine 2013
Frontier
Pemvidutide
ALT-801 · 1:1 GLP-1/Glucagon Dual
UK · legal to buy or possess
·Weight loss · MASH · AUD
·Once weekly SubQ · 1.2–2.4 mg
·Phase 2b done · BTD MASH
Frontier
Mazdutide
IBI362 · GLP-1/Glucagon Dual
UK · legal to buy or possess
·Weight loss · liver fat · T2D
·4–6 mg · SubQ · weekly
·China-approved · GLORY-1 Ph3
Frontier
Cagrilintide
AM833 · Amylin Analogue
UK · legal to buy or possess
·Weight loss · satiety · amylin
·2.4 mg · SubQ · weekly
·Phase 3 mono · CagriSema base
Coming Soon
MariTide
AMG 133 · GLP-1 / GIP-Antagonist
GLP-1 agonist · GIP antagonist
~20% loss · Phase 2 · NEJM 2025
Monthly dosing · Phase 3 enrolling